Arina Rodionova is the only Australian left in either singles draw at Wimbledon after a disappointing day in London. The Australians in action fought hard but were ultimately no match for their opponents.

Rodionova earned victory the hard way, saving seven match points against 16th seed Anastasia Pavlyuchenkova in a career-defining match.

The horror day for Australia looked set to continue when Pavlyuchenkova breezed through the first set in just over half an hour.

But Rodionova settled and held her nerve to claim her first victory in the main draw of a Grand Slam 3-6, 7-6(6), 9-7.

She will face Kazakh wildcard Zarina Diyas, who is ranked 36 places above her.

On the men's side, Adelaide-born Thanasi Kokkinakis went down to a rampant Juan Martin Del Potro, who looked eager to make up for lost time, in four tough sets.

The 29th seeded Argentinian breezed through the first set before the momentum shifted to the 21-year-old Australian in the second, which he was able to win 6-3. Kokkinakis put up a fight, losing the third set in a tie-break, depite going up a break early in the set.

But Del Potro's experience and class was no match for Kokkinakis, who went down in four tough sets 6-3, 3-6, 7-6(2), 6-4.

On Court five, Jordan Thompson was unable to continue his impressive grass court form, going down to Spaniard Albert Ramos-Vinolas, 6-4, 6-4, 7-6(4).

Fresh from beating reigning Wimbledon champion, Andy Murray, in the Queen's Club lead-up tournament, Thompson was unable to replicate that form against the 25th seed.

It was Thompson's serve which hastened his demise, only making 56 percent of first serves, compared to his opponent's 75 percent.

From there, he could only win 48 percent of points from his second serve, a figure not even an all time great like Roger Federer could recover from.

Enigmatic young Aussie Bernard Tomic could not handle big serving German, Mischa Zverev, who sent down 18 aces in a straight forward win over the Australian.

Zverev's serve was lethal. He never allowed Tomic a chance to break and only allowed him to win a meagre eight points receiving.

But the match was not without controversy after Tomic later admitted to faking an injury to call an injury time-out. Tournament organisers generally take a dim view to this and are said to be investigating the incident.

Daria Gavrilova entered Wimbledon as the top ranked Australian female. With the weight of a nation on her shoulders, she could not produce the kind of performance which has taken her to the second week of the Australian Open on two occasions.

The 20th seed was defeated by Croatian qualifier, Petra Martic, in three sets.

Gavrilova started slowly, losing the first set 6-4, before rallying to win the second 2-6, despite serving at a disappointing 56 percent.

The final set was hard fought, taking just under 80 minutes but the honours ultimately went to the 26-year-old Croatian, winning it 10-8 and with it, a ticket to the second round.

With only one Australian remaining in either singles draw, tennis fans will be looking forward to the end of the grass court season and the beginning of hard courts, a surface more familiar for many Australian players.

The doubles tournament begins soon with several Australians in action including top seed John Peers, Anastasia and Arina Rodionova, Ashleigh Barty and Casey Dellacqua.